HCG (Human Chorionic Gonadotropin)
Gonadotropin glycoprotein reference standard for in-vitro receptor research. A two-subunit glycoprotein (α/β) structurally homologous to LH, used in LH/CG receptor-binding assays and HPG-axis signaling studies in cell-culture systems. Purity ≥99% by HPLC/MS. For research use only.
Free COA included · Free shipment protection · 99%+ purity by HPLC & MS · Lyophilized powder
Certificate of Analysis — Included Free
Every batch independently tested by U.S.-accredited labs. Lot-matched COA confirms identity, purity ≥99% by HPLC, and safety screening.
Research Overview
HCG (Human Chorionic Gonadotropin) is a glycoprotein composed of two non-covalently associated subunits — an α subunit shared with LH, FSH, and TSH, and a unique β subunit that confers specificity for the LH/CG receptor. Supplied as a lyophilized reference standard for in-vitro receptor research.
In receptor-binding assays and cell-culture studies, HCG has been characterized as an LH/CG receptor ligand with extended receptor-binding kinetics relative to endogenous LH. Research applications include LH/CG receptor characterization, HPG-axis signaling pathway studies in cell models, and analytical method development for glycoprotein hormone quantification.
The β-subunit's unique C-terminal extension relative to LH confers extended receptor-binding kinetics — a structural property examined in comparative receptor-binding assays. Identity and purity are confirmed by HPLC and LC-MS prior to dispatch.
Research framing: Sold for research use only. Not approved for any human therapeutic application.
Molecular Information
| Full Name | HCG (Human Chorionic Gonadotropin) |
| CAS Number | 9002-61-3 |
| Molecular Formula | Glycoprotein (α and β subunits) |
| Molecular Weight | ~36,700 g/mol |
| Sequence / Structure | Two-subunit glycoprotein: α subunit (92 aa) shared with LH/FSH/TSH; β subunit (145 aa) unique to HCG |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or dilute acetic acid |
| Format | Lyophilized (freeze-dried) powder |
| SKU | CL-046 |
Quality & Testing
- Purity: ≥99% by HPLC
- Identity: Confirmed by Mass Spectrometry (LC-MS)
- Heavy Metals: Screened; below detection thresholds
- Endotoxin: Tested per LAL assay
- Lot Tracking: Lot number on every vial matches published COA
- Packaging: Nitrogen-purged, sealed glass vials
Storage & Handling
- Short-term: Room temperature (15–25°C), dry, dark — up to 4 weeks
- Long-term: Refrigerated at 2–8°C — up to 18 months lyophilized
- Extended: −20°C; avoid freeze-thaw cycling
- After reconstitution: stable 14–21 days at 4°C; avoid repeated freeze-thaw.
This compound is supplied for in vitro research and laboratory use only. It is not for human or veterinary use, is not a drug or dietary supplement, and has not been evaluated or approved by the FDA or any regulatory agency for any therapeutic application. Purchasers must be 18 years of age or older and qualified researchers operating in compliance with all applicable local, state, and federal regulations governing research chemicals.
