CL-Mz
Synthetic peptide reference standard (IBI362/LY3305677) for in-vitro receptor-binding research. Oxyntomodulin-derived fatty-acid conjugate characterized by dual receptor-binding activity in cell-based assay systems. Purity ≥99% by HPLC/MS. For research use only.
Free COA included · Free shipment protection · 99%+ purity by HPLC & MS · Lyophilized powder
Certificate of Analysis — Included Free
Every batch independently tested by U.S.-accredited labs. Lot-matched COA confirms identity, purity ≥99% by HPLC, and safety screening.
Research Overview
CL-Mz is a fatty-acid conjugated synthetic peptide (IBI362/LY3305677) structurally derived from oxyntomodulin — a naturally occurring peptide from intestinal L-cells. It is supplied as a lyophilized reference standard for in-vitro receptor-binding research and analytical method development.
In cell-based assay systems, CL-Mz has been studied for its receptor-binding profile across multiple GPCR targets. The fatty acid conjugation extends plasma half-life through albumin binding, a property examined in pharmacokinetic characterization studies. These findings are from in-vitro and preclinical biochemical assays only.
Researchers use CL-Mz as a reference compound in receptor-selectivity panels and structural characterization work. Purity is confirmed by HPLC and LC-MS prior to dispatch.
Research framing: Sold for research use only. Not approved for any human therapeutic application.
Molecular Information
| Full Name | CL-Mz (IBI362/LY3305677) |
| CAS Number | 2413942-80-8 |
| Molecular Formula | C₁₅₁H₂₃₁N₃₉O₅₂S |
| Molecular Weight | 3,418.8 g/mol |
| Sequence / Structure | Oxyntomodulin-derived synthetic peptide; fatty acid conjugate |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or dilute acetic acid |
| Format | Lyophilized (freeze-dried) powder |
| SKU | CL-051 |
Quality & Testing
- Purity: ≥99% by HPLC
- Identity: Confirmed by Mass Spectrometry (LC-MS)
- Heavy Metals: Screened; below detection thresholds
- Endotoxin: Tested per LAL assay
- Lot Tracking: Lot number on every vial matches published COA
- Packaging: Nitrogen-purged, sealed glass vials
Storage & Handling
- Short-term: Room temperature (15–25°C), dry, dark — up to 4 weeks
- Long-term: Refrigerated at 2–8°C — up to 18 months lyophilized
- Extended: −20°C; avoid freeze-thaw cycling
- After reconstitution: stable 14–21 days at 4°C; avoid repeated freeze-thaw.
This compound is supplied for in vitro research and laboratory use only. It is not for human or veterinary use, is not a drug or dietary supplement, and has not been evaluated or approved by the FDA or any regulatory agency for any therapeutic application. Purchasers must be 18 years of age or older and qualified researchers operating in compliance with all applicable local, state, and federal regulations governing research chemicals.
