HGH 191AA (Somatropin)
191-amino-acid recombinant growth-hormone reference standard for in-vitro assay use. Full-sequence single-chain polypeptide identical to endogenous pituitary GH, with two disulfide bridges. Identity confirmed by SDS-PAGE, RP-HPLC, and LC-MS. Used in GH-receptor binding assays, JAK/STAT signaling pathway studies, and analytical method development. For research use only.
Free COA included · Free shipment protection · 99%+ purity by HPLC & MS · Lyophilized powder
Certificate of Analysis — Included Free
Every batch independently tested by U.S.-accredited labs. Lot-matched COA confirms identity, purity ≥99% by HPLC, and safety screening.
Research Overview
HGH 191AA is a recombinant human growth hormone produced via recombinant DNA technology. It consists of the same 191-amino-acid single-chain polypeptide sequence as endogenous pituitary-derived growth hormone, with two disulfide bridges. Supplied as a lyophilized reference standard for in-vitro assay use.
In in-vitro and preclinical research, this reference standard has been used in GH-receptor binding assays, JAK2/STAT5 signaling pathway characterization, and analytical method development. It binds to the GH receptor, triggering JAK2/STAT5 signaling and downstream signaling cascades primarily in hepatic cell models — studied at the molecular level in cell-culture systems.
The "191AA" designation refers to the complete amino acid chain, distinguishing it from shorter-sequence analogues and truncated fragments. Research purity is confirmed by SDS-PAGE, RP-HPLC, and LC-MS prior to dispatch.
Research framing: Sold for research use only. Not approved for any human therapeutic application.
Molecular Information
| Full Name | HGH 191AA (Somatropin) |
| CAS Number | 12629-01-5 |
| Molecular Formula | C₉₉₀H₁₅₂₈N₂₆₂O₃₀₀S₇ |
| Molecular Weight | 22,124 g/mol |
| Sequence / Structure | 191 amino acid single-chain polypeptide (identical sequence to endogenous human growth hormone) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or dilute acetic acid |
| Format | Lyophilized (freeze-dried) powder |
| SKU | CL-044 |
Quality & Testing
- Purity: ≥99% by HPLC
- Identity: Confirmed by Mass Spectrometry (LC-MS)
- Heavy Metals: Screened; below detection thresholds
- Endotoxin: Tested per LAL assay
- Lot Tracking: Lot number on every vial matches published COA
- Packaging: Nitrogen-purged, sealed glass vials
Storage & Handling
- Short-term: Room temperature (15–25°C), dry, dark — up to 4 weeks
- Long-term: Refrigerated at 2–8°C — up to 18 months lyophilized
- Extended: −20°C; avoid freeze-thaw cycling
- After reconstitution: stable 14–21 days at 4°C; avoid repeated freeze-thaw.
This compound is supplied for in vitro research and laboratory use only. It is not for human or veterinary use, is not a drug or dietary supplement, and has not been evaluated or approved by the FDA or any regulatory agency for any therapeutic application. Purchasers must be 18 years of age or older and qualified researchers operating in compliance with all applicable local, state, and federal regulations governing research chemicals.
