Oxytocin Acetate
The nonapeptide neurohormone produced by hypothalamic paraventricular and supraoptic nuclei. A disulfide-bridged cyclic peptide that acts at oxytocin receptors (OXTR). Studied in social behavior neuroscience, HPA axis research, smooth muscle pharmacology, and neuroendocrine signaling.
Free COA included · Free shipment protection · 99%+ purity by HPLC & MS · Lyophilized powder
Certificate of Analysis — Included Free
Every batch independently tested by U.S.-accredited labs. Lot-matched COA confirms identity, purity ≥99% by HPLC, and safety screening.
Research Overview
Oxytocin (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂) is a cyclic nonapeptide neurohormone synthesized in magnocellular neurons of the hypothalamic paraventricular and supraoptic nuclei. It is released both peripherally (posterior pituitary → bloodstream) and centrally (dendrites, axon terminals) and acts at the oxytocin receptor (OXTR), a Gq-coupled GPCR widely distributed in the brain, uterus, mammary gland, and cardiovascular tissue.
In vitro receptor pharmacology research has characterized oxytocin's binding kinetics and signal transduction at OXTR compared to its structural analogue vasopressin and the vasopressin receptor subtypes V1a, V1b, and V2. Receptor selectivity studies have used radiolabeled and fluorescent oxytocin analogues to map OXTR distribution in CNS tissue preparations.
Neuroscience research has employed oxytocin in hypothalamic slice preparations, primary hippocampal neuron cultures, and ex vivo brain perfusion models to study its role in GABAergic signaling modulation, neuroplasticity, and HPA axis feedback. Smooth muscle pharmacology studies have used it in uterine strip contraction assays.
All referenced studies are preclinical or in vitro. Not for human use.
Molecular Information
| Full Name / IUPAC | Oxytocin Acetate |
| CAS Number | 50-56-6 |
| Molecular Formula | C₄₃H₆₆N₁₂O₁₂S₂ |
| Molecular Weight | 1,007.19 g/mol |
| Sequence / Structure | Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂ (Cys1-Cys6 disulfide) |
| Appearance | White lyophilized powder |
| Solubility | Soluble in sterile water or 0.9% saline |
| Format | Lyophilized (freeze-dried) powder |
| SKU | CL-026 |
Quality & Testing
- Purity: ≥99% by HPLC
- Identity: Confirmed by Mass Spectrometry (LC-MS)
- Heavy Metals: Screened; below detection thresholds
- Endotoxin: Tested per LAL assay
- Lot Tracking: Lot number on every vial matches published COA
- Packaging: Nitrogen-purged, sealed glass vials
Storage & Handling
- Short-term: Room temperature (15–25°C), dry, dark — up to 4 weeks
- Long-term: Refrigerated at 2–8°C — up to 18 months lyophilized
- Extended: −20°C; avoid freeze-thaw cycling
- Store at −20°C. Reconstituted: stable 14 days at 4°C; disulfide bond is stable under normal storage conditions.
This compound is supplied for in vitro research and laboratory use only. It is not for human or veterinary use, is not a drug or dietary supplement, and has not been evaluated or approved by the FDA or any regulatory agency for any therapeutic application. Purchasers must be 18 years of age or older and qualified researchers operating in compliance with all applicable local, state, and federal regulations governing research chemicals.
