SLU-PP-332
SLU-PP-332 is a small-molecule pan-agonist of the estrogen-related receptors (ERRα, ERRβ, ERRγ) that has been studied as an "exercise mimetic" in metabolic and mitochondrial research. In preclinical rodent and cell models it has been examined for its effects on oxidative metabolism, mitochondrial biogenesis, and energy-expenditure pathways without physical activity.
Free COA included · Free shipment protection · 99%+ purity by HPLC & MS · Lyophilized powder
Certificate of Analysis — Included Free
Every batch independently tested by U.S.-accredited labs. Lot-matched COA confirms identity, purity ≥99% by HPLC, and safety screening.
Research Overview
SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptors (ERRs), a family of orphan nuclear receptors — ERRα, ERRβ, and ERRγ — that act as master regulators of oxidative metabolism and mitochondrial function. It was developed and characterized in academic metabolic-pharmacology research and is frequently referred to as an "exercise mimetic" because it activates many of the same transcriptional programs associated with endurance exercise.
In published preclinical work, SLU-PP-332 has been studied for its effects on mitochondrial biogenesis, fatty-acid oxidation, and energy expenditure in rodent and cell-culture models. Research has examined ERR-driven gene-expression signatures, oxidative-fiber phenotypes in skeletal muscle, and whole-body metabolic parameters in animal models, all without changes in physical activity or food intake.
The compound is supplied as a research chemical for in vitro and preclinical receptor-pharmacology, metabolic, and mitochondrial studies.
All referenced studies are preclinical or in vitro. Not for human use.
Molecular Information
| Name | SLU-PP-332 |
| Compound Class | Small-molecule pan-ERR (estrogen-related receptor) agonist |
| Receptor Targets | ERRα · ERRβ · ERRγ |
| CAS Number | N/A (research compound) |
| Appearance | Lyophilized powder |
| Solubility | Soluble in DMSO; sparingly soluble in aqueous buffers |
| Format | Lyophilized (freeze-dried) powder |
| SKU | CL-073 |
Quality & Testing
- Purity: ≥99% by HPLC
- Identity: Confirmed by Mass Spectrometry (LC-MS)
- Heavy Metals: Screened; below detection thresholds
- Residual Solvents: Tested per ICH guidance
- Lot Tracking: Lot number on every vial matches published COA
- Packaging: Nitrogen-purged, sealed glass vials
Storage & Handling
- Short-term: Room temperature (15–25°C), dry, dark — up to 4 weeks
- Long-term: Refrigerated at 2–8°C — up to 18 months lyophilized
- Extended: −20°C; avoid freeze-thaw cycling
- Store at −20°C. Reconstitute in DMSO or appropriate research solvent; aliquot to avoid freeze-thaw.
This compound is supplied for in vitro research and laboratory use only. It is not for human or veterinary use, is not a drug or dietary supplement, and has not been evaluated or approved by the FDA or any regulatory agency for any therapeutic application. Purchasers must be 18 years of age or older and qualified researchers operating in compliance with all applicable local, state, and federal regulations governing research chemicals.
Certificate of Analysis
Independent third-party test results from Janoshik Analytical. Click any CoA to view full-size.
